Products

Current product lines of NVIGEN's technology:


  • MagVigen™ | Magnetic nanoparticles for immunoprecipitation, molecular and cellular purification and identification.
  • MaxVigen™ | Multifunctional nanoparticles for in vivo targeted delivery and imaging.
  • MyQuVigen™ | Combination of magnetic nanoparticles and quantum dots for imaging, manipulation and detection.
  • AuVigen™ | Biocompatible gold nanoparticles for biological sensing, imaging and therapeutic applications.

NVIGEN designs and engineers our nanoparticles and surface conjugations. Our ready-to-use nanoparticle reagents are compatible and ideal for experimental workflows, molecular imaging, IVD and therapeutics. We also offer services that can customize nanoparticles with specific surface functional groups to bind specific ligands.

Our most popular product for protein co-immunoprecipitation comes from our MagVigen™ platform. MagVigen™ nanoparticles have strong magnetism, sensitivity and binding specificity. We are able to customize and fine-tune surface conjugation and particle functionalities, making MagVigen™ ideal for use in a wide variety or applications. Magnetic separation is fast yet gentle, causing minimal disruption to your target proteins, permitting the isolation and preservation of labile compositions and conformations that might otherwise being interfered. See below for more in-depth descriptions of our magnetic beads and how they can assist you in your research.



MagVigenTM


Magnetic nanoparticle beads with high magnetic response and binding specificity.

MagVigenTM magnetic nanoparticle beads easily respond to an external magnet. MagVigenTM is one of our top selling magnetic bead products a which has maximum versatility in its usages. View our infographic how-to guide for working with magnetic beads.

Advantages of MagVigenTM magnetic nanoparticle beads:

  • Magnetic separation is simple and fast. No columns or centrifugation needed.
  • No residual magnetism when magnetic field is removed.
  • Nano-size beads minimize interference within interacting complexes.
  • High recovery rate and performance consistency.
  • High capacity and elution efficiency.
  • Enable novel biomarker identification.
  • Economical.

Applications of MagVigenTM magnetic nanoparticle beads:

  • Protein-antibody purification
  • Immunoprecipitation
  • Chromatin immunoprecipitation
  • DNA and RNA purification
  • Cell separation and enrichment
  • Molecular enrichment

Three easy steps using MagVigen™ - protein A nanoparticles for protein enrichment and purification:

  1. Bind: When mixed with a sample, MagVigen™ nanoparticles bind to the desired target (i.e. cells, pathogenic microorganisms, nucleic acids, peptides, proteins or protein complexes, etc). This interaction relies on the specific affinity of the ligand conjugated to the surface of the nanoparticles. NVIGEN engineers desired surface conjugations.
  2. Wash: The beads respond to a magnetic force (by use of a magnet), allowing bound material to be rapidly and efficiently separated from the rest of the sample. After unbound materials are removed by aspiration, the nanoparticle-bound targets are washed by using the magnet.
  3. Elute: The bound target is released from the nanoparticle and can be used for downstream applications.

Download the technical information for MagVigen™ - Protein A/G nanoparticles. MagVigen™ - Protein A/G can be used for molecular purification, immunoprecipitation, and new biomarker or protein interaction identification.

Download the technical information for MagVigen™ - Streptavidin nanoparticles.  MagVigen™ - Streptavidin can be used as a simple and efficient method for gentle cell separation.

Download the technical information for MagVigen™ - SH/-NH2 nanoparticles. MagVigen™ - SH/-NH2 offers the flexibility to functionalize magnetic nanoparticles for specific applications.



MyQuVigenTM


A unique combination of magnetic and fluorescent properties into one functional nanoparticle bead.

Isolation and concurrent staining of human cancer cells with green or red fluorescence MyQuVigenTM - streptavidin nanoparticle beads.

Advantages of MyQuVigenTM fluorescent magnetic nanoparticle beads:

  • Concurrent magnetic separation and fluorescent labeling.
  • High magnetic response
  • Bright stable fluorescence
  • Superior multiplexing capability
  • Perfect for molecular and cellular imaging and detection

Applications of MyQuVigenTM fluorescent mangetic nanoparticle beads:

  • Multiplexed diagnostic assays
  • High sensitivity biodetection
  • Magnetic actuation
  • Cellular separation and imaging



MaxVigenTM


Multifunctional nanoparticle beads for in vivo imaging, targeting and drug delivery applications.

Tumor neovasculature imaged using MaxVigenTM NIR fluorescence.

Advantages of MaxVigenTM multifunctional nanoparticle beads:

  • Superior detection sensitivity through fluorescence and/or MRI
  • Highly enhanced permeability and retention effect
  • 35 Days of cancer region observation window, 600% increase compared to other commercial products.

Applications of MaxVigenTM multifunctional nanoparticle beadss:

  • Vasculature/cancer/inflammation imaging
  • Molecular imaging and targeting
  • Multimodality fluorescence and magnetic resonance imaging
  • Combined molecular imaging and drug delivery
  • In vitro and in vivo imaging of molecular interactions



AuVigenTM


Gold nanoparticle beads with superior biocompatibility.

Nanoparticle stability evaluated with increased salt concentration. Other commercial Au nanoparticles have much less salt tolerance, indicated by the purple color formed by nanoparticle aggregation.

Advantages of AuVigenTM gold nanoparticle beads:

  • Distinct surface plasmon features
  • Stable and tailorable surfaces
  • Tunable sizes
  • Multiplexing based on SPR property
  • Suitable as injectable reagents for in vivo imaging and therapeutic research

Applications of AuVigenTM gold nanoparticle beads:

  • Immuno staining and detection
  • Protein crystallography tag
  • SERS substrate
  • Making Bio-conjugates of Au nanoparticle beads with DNA, RNA or proteins
  • In vitro molecular imaging, drug delivery or photo thermal therapy



MagVigen™ Protein A/G Nanoparticles - Product sheet 1

MagVigen™ Protein A/G nanoparticles are ideal for antibody purification and immunoprecipitation assays...
>> Read More

MagVigen™ Streptavidin Nanoparticles - Product sheet 2

MagVigen™ Streptavidin magnetic nanoparticles can universally bind to any biotinylated biomolecules ...
>> Read More

MagVigen™ - anti-FLAG Nanoparticles - Product sheet 3

MagVigen™ - anti-FLAG nanoparticles are ideal for the purification of FLAG tagged recombinant proteins ...
>> Read More

MyQuVigen™ - anti-mouse IgG,
emi 635 nm - Product sheet 4

MyQuVigen™ nanoparticles are unique combination of SPIO and quantum dots ...
>> Read More

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Special order, call 408-970-9988